Sarcomatoid Mesothelioma

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The types of symptoms a patient with sarcomatoid mesothelioma may experience will depend on where specifically the cancer develops. Sarcomatoid pleural mesothelioma involves the lungs, which will typically lead to chronic chest pain and difficulty breathing. Sarcomatoid peritoneal mesothelioma cases are rarer and involve the abdominal lining.

  • Chest pain
  • Excess fluid in the lungs or abdomen
  • Loss of appetite
  • Nausea
  • Vomiting
  • Difficulty breathing
  • Frequent coughing (including coughing up blood)
  • Lumps under the skin
  • Unexplained weight loss

If any combination of sarcomatoid mesothelioma symptoms persists for weeks and you know you have previously been exposed to asbestos, you should consider getting screened for this disease. Getting an accurate diagnosis can be hard due to the disease’s resemblance to other more common conditions. You may need to seek out a mesothelioma specialist if your doctor is not familiar with this type of cancer or does not want to order a biopsy.

A biopsy is the most reliable way to confirm a diagnosis of sarcomatoid mesothelioma. During a biopsy, a small sample of tissue will be taken and studied under a microscope. The presence of asbestos fibers in this tissue or abnormal cell growth patterns can indicate the presence of sarcomatoid mesothelioma. A biopsy also allows doctors to determine how aggressive the disease is and what types of treatments may be most effective. In many cases, biopsies are used to confirm diagnoses made with imaging technologies like CT scans and X-rays. However, since these technologies cannot always detect all aspects of sarcomatoid mesothelioma, a biopsy is often necessary to gain definitive answers.

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Unfortunately, there is no cure for sarcomatoid mesothelioma. This rarer type of mesothelioma is usually diagnosed in the late stages, making it difficult to treat and impossible to cure. Treatment options for sarcomatoid mesothelioma may include a combination of chemotherapy, radiation therapy, immunotherapy, or targeted therapy. The goal of treatment is typically to provide symptom relief and improve the quality of life for patients. Alternative therapies such as nutritional supplements and herbal remedies are also sometimes used to help manage symptoms in people with sarcomatoid mesothelioma. Despite advances in treatments and medications, survival rates remain poor, and this type of cancer remains incurable.

Due to its uniquely aggressive nature, sarcomatoid mesothelioma usually requires comprehensive treatments that combine surgery with chemotherapy or radiation therapy. Chemotherapy is one of the most common treatments used to help manage this disease. It can be used alone or in combination with other treatments to try to slow down tumor growth and reduce symptoms, relieving the patient and potentially extending their life expectancy by several months.

While radiation therapy has not been proven to be an effective primary treatment option for this type of cancer, it may still play a role in helping patients with sarcomatoid mesothelioma achieve better outcomes. Radiation therapy works by targeting tumor cells with high doses of X-ray or other forms of ionizing radiation in order to kill them off or prevent them from growing further. In some cases, it can also shrink tumors or reduce symptoms such as pain associated with the disease. Depending on the location and size of the tumor(s), doctors may use external beam radiotherapy (EBRT) or brachytherapy (where radioactive sources are placed directly into body cavities). Additionally, newer techniques like stereotactic radiosurgery (SRS) have shown promise in treating certain types of sarcomatoid mesotheliomas that cannot be surgically removed.

Immunotherapy has also been used with some success in reducing the severity of sarcomatoid mesothelioma symptoms. Immunotherapy works by stimulating a patient’s immune system response so it can recognize and attack cancer cells more effectively. This type of therapy has been found to help slow tumor growth and relieve symptoms associated with sarcomatoid mesothelioma, such as pain, fatigue, fever, and difficulty breathing.

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