Epithelioid Mesothelioma

X-ray image of a human chest showing ribs, spine, and lungs, with a hand pointing at the screen.

While constant fevers and fluid buildup are two of the most common symptoms associated with epithelioid mesothelioma, a patient’s precise symptoms will vary based on several factors, including their overall health, their age, the cancer’s cell type, and where the tumor specifically develops. Again, many patients only experience noticeably severe symptoms at the latest stages of the disease. 

  • Chest pain
  • Difficulty breathing
  • Fluid buildup in the lungs
  • Coughing
  • Fever
  • Sudden weight loss
  • Abdominal pain and swelling
  • Fever
  • Loss of appetite
  • Constipation
  • Fluid buildup in the abdomen
  • Sudden weight loss

The symptoms of epithelioid mesothelioma are similar or identical to a range of other diseases, including other cancers and even the flu. This can make getting an accurate diagnosis very difficult, as mesothelioma is rare, and many doctors are not experienced in recognizing its symptoms. This makes emphasizing any known history of asbestos exposure extremely important, as it is one of the key causes of this cancer. You should tell your doctor about any work in professions that may have exposed you to asbestos, even if you are not aware of any confirmed exposure. 

If your doctor is reluctant to specifically test you for epithelioid mesothelioma, it is in your best interest to seek out a cancer center or a mesothelioma expert. These doctors can run several basic tests to rule out similar diseases before proceeding with more targeted diagnostic tools, such as chest x-rays and CT scans, that can get you closer to an accurate diagnosis. Then, a biopsy can confirm the diagnosis.  

A biopsy involves collecting a sample of cells or tissue from the affected area for microscopic examination under a microscope by pathologists (doctors who specialize in diagnosing diseases). This allows them to determine whether or not cancerous cells are present and if they are consistent with epithelial mesothelioma. In some cases, additional tests such as imaging scans may be needed to confirm the diagnosis before treatment begins.

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  • “SWMW did an amazing job! They started the process with my father but during the process my father passed. They were so helpful when it came to us, his children, taking over in place of my dad. They answered every call and were extremely patient and supportive of us. They really did a great job with keeping us informed and educated. They fought for us. I would recommend them to anyone that hears the diagnosis of Mesothelioma. They will fight for you 100% of the way. Thank you SWMW Team for your support and patience! We truly appreciate all of you! – The Anderson’s”

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To date, there is unfortunately no effective cure for epithelioid mesothelioma. The prognosis for this type of cancer varies depending on many factors such as the patient’s age and overall health status as well as the stage at which it was diagnosed. Unfortunately, due to its aggressive nature and difficulty in diagnosis, epithelioid mesothelioma is usually only discovered after it has reached an advanced stage with few treatment options available. Treatment is intended to ease the symptoms suffered by the patient and marginally increase their life expectancy.

After evaluating radiographs and pathology reports, a doctor may recommend targeted treatments such as chemotherapy, radiation therapy, or surgery depending on how advanced the tumor is and its location in the body. Treatment options are limited due to this cancer’s aggressiveness and its general resistance to traditional therapies. Epithelioid mesothelioma is generally easier to treat than other types of mesotheliomas, however.

Treatment for epithelioid mesothelioma typically involves chemotherapy combined with surgery where possible. Surgery may be curative (though it can almost never actually cure the cancer, just help you live longer) or palliative (which is designed to ease or prevent the symptoms). These surgeries typically involve efforts to remove cancerous tissue from the lungs and surrounding areas.

Chemotherapy and immunotherapy are also treatment options for epithelioid mesothelioma. They may be pursued individually or combined with surgery. Chemotherapy involves using powerful drugs to kill cancer cells and shrink tumors. It may be used as palliative treatment to reduce symptoms such as pain or shortness of breath and can extend life expectancy for those who are not candidates for surgery. Alternatively, by using immunotherapies (including checkpoint inhibitors or CAR-T cell therapies), doctors may be able to target specific areas affected by epithelioid mesothelioma with greater accuracy and fewer side effects than standard treatments.

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